Pub. Date : 2019 Apr 1
PMID : 30590152
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The secretion and gene expression of NO/iNOS, IL-6 and TNF-alpha in APS-induced macrophage cell were significantly enhanced. | aps | tumor necrosis factor | Mus musculus |
| 2 | However, APS-induced TNF-alpha production was decreased by blocking the MAPK or NF-kappaB signaling pathways, especially for the blockade of p38. | aps | tumor necrosis factor | Mus musculus |
| 3 | Therefore, we demonstrated that APS could improve the immune functions of RAW 264.7 macrophages cells by promoting the cell viability and increasing secretion and gene expressions of NO/iNOS, IL-6 and TNF-alpha through the MAPK and NF-kappaB signaling pathways. | aps | tumor necrosis factor | Mus musculus |