PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30590152-6 2019 The secretion and gene expression of NO/iNOS, IL-6 and TNF-alpha in APS-induced macrophage cell were significantly enhanced. aps 68-71 tumor necrosis factor Mus musculus 55-64 30590152-7 2019 However, APS-induced TNF-alpha production was decreased by blocking the MAPK or NF-kappaB signaling pathways, especially for the blockade of p38. aps 9-12 tumor necrosis factor Mus musculus 21-30 30590152-9 2019 Therefore, we demonstrated that APS could improve the immune functions of RAW 264.7 macrophages cells by promoting the cell viability and increasing secretion and gene expressions of NO/iNOS, IL-6 and TNF-alpha through the MAPK and NF-kappaB signaling pathways. aps 32-35 tumor necrosis factor Mus musculus 201-210