Title : lncRNA MALAT1 binds chromatin remodeling subunit BRG1 to epigenetically promote inflammation-related hepatocellular carcinoma progression.

Pub. Date : 2019

PMID : 30546959






1 Functional Relationships(s)
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1 Mechanistically, MALAT1 recruited Brahma-related gene 1 (BRG1), a catalytic subunit of chromatin remodeling complex switching/sucrose non-fermentable (SWI/SNF), to the promoter region of IL-6 and CXCL8, and thus facilitated NF-kappaB to induce the expression of these inflammatory factors. Sucrose interleukin 6 Homo sapiens