Pub. Date : 2019 Jan
PMID : 30520054
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, we examined the role of metformin in nuclear factor kappa B (NF-kappaB)-mediated inflammatory responses in HaCaT cells, a cell line for the keratinocyte. | Metformin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | In the present study, we examined the role of metformin in nuclear factor kappa B (NF-kappaB)-mediated inflammatory responses in HaCaT cells, a cell line for the keratinocyte. | Metformin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | Immunofluorescence staining and western blot analysis showed that metformin inhibited the nuclear localization of p65, a subunit of nuclear factor NF-kappaB. | Metformin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 4 | In addition, metformin suppressed the transcription activity of NF-kappaB by inhibiting the degradation of IkappaBalpha. | Metformin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 5 | The inhibitory effect of metformin on NF-kappaB signalling is comparable with a specific IKKbeta inhibitor BI605906. | Metformin | nuclear factor kappa B subunit 1 | Homo sapiens |