Title : Anti-melanogenesis potential of a new series of Morita-Baylis-Hillman adducts in B16F10 melanoma cell line.

Pub. Date : 2019 Mar

PMID : 30476649






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1 Additionally we have found that (1a, 2b and 3f) compounds had a strong melanogenesis inhibition effect in isobutylmethylxanthine (IBMX)-treated murine melanoma B16F10 cells when tested at low and non cytotoxic dose (10-50 microM), by attenuating the melanin production, intracellular tyrosinase activity and tyrosinase expression. 1-Methyl-3-isobutylxanthine tyrosinase Mus musculus
2 Additionally we have found that (1a, 2b and 3f) compounds had a strong melanogenesis inhibition effect in isobutylmethylxanthine (IBMX)-treated murine melanoma B16F10 cells when tested at low and non cytotoxic dose (10-50 microM), by attenuating the melanin production, intracellular tyrosinase activity and tyrosinase expression. 1-Methyl-3-isobutylxanthine tyrosinase Mus musculus
3 Additionally we have found that (1a, 2b and 3f) compounds had a strong melanogenesis inhibition effect in isobutylmethylxanthine (IBMX)-treated murine melanoma B16F10 cells when tested at low and non cytotoxic dose (10-50 microM), by attenuating the melanin production, intracellular tyrosinase activity and tyrosinase expression. 1-Methyl-3-isobutylxanthine tyrosinase Mus musculus
4 Additionally we have found that (1a, 2b and 3f) compounds had a strong melanogenesis inhibition effect in isobutylmethylxanthine (IBMX)-treated murine melanoma B16F10 cells when tested at low and non cytotoxic dose (10-50 microM), by attenuating the melanin production, intracellular tyrosinase activity and tyrosinase expression. 1-Methyl-3-isobutylxanthine tyrosinase Mus musculus