Protein Name tyrosinase
Organism Mus musculus
Gene ID 22173
Gene Symbol

Tyr

UniProt P11344 (TYRO_MOUSE), Q91XK0 (Q91XK0_MOUSE)
Relationships Total Number of functionally related compound(s) : 808
Total Number of Articles : 800
Description

tyrosinase

Gene Summary

Enables protein homodimerization activity. Acts upstream of or within several processes, including melanin biosynthetic process; pigmentation; and thymus development. Located in melanosome. Is expressed in central nervous system; eye; head mesenchyme; mesenchyme derived from neural crest; and skin. Used to study buphthalmos and oculocutaneous albinism. Human ortholog(s) of this gene implicated in several diseases, including melanoma (multiple); ocular albinism 1; oculocutaneous albinism (multiple); retinoschisis; and vitiligo. Orthologous to human TYR (tyrosinase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • tyrosinase
  • albino locus protein
  • monophenol monooxygenase
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Properties