PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30476649-7 2019 Additionally we have found that (1a, 2b and 3f) compounds had a strong melanogenesis inhibition effect in isobutylmethylxanthine (IBMX)-treated murine melanoma B16F10 cells when tested at low and non cytotoxic dose (10-50 microM), by attenuating the melanin production, intracellular tyrosinase activity and tyrosinase expression. 1-Methyl-3-isobutylxanthine 106-128 tyrosinase Mus musculus 284-294 30476649-7 2019 Additionally we have found that (1a, 2b and 3f) compounds had a strong melanogenesis inhibition effect in isobutylmethylxanthine (IBMX)-treated murine melanoma B16F10 cells when tested at low and non cytotoxic dose (10-50 microM), by attenuating the melanin production, intracellular tyrosinase activity and tyrosinase expression. 1-Methyl-3-isobutylxanthine 106-128 tyrosinase Mus musculus 308-318 30476649-7 2019 Additionally we have found that (1a, 2b and 3f) compounds had a strong melanogenesis inhibition effect in isobutylmethylxanthine (IBMX)-treated murine melanoma B16F10 cells when tested at low and non cytotoxic dose (10-50 microM), by attenuating the melanin production, intracellular tyrosinase activity and tyrosinase expression. 1-Methyl-3-isobutylxanthine 130-134 tyrosinase Mus musculus 284-294 30476649-7 2019 Additionally we have found that (1a, 2b and 3f) compounds had a strong melanogenesis inhibition effect in isobutylmethylxanthine (IBMX)-treated murine melanoma B16F10 cells when tested at low and non cytotoxic dose (10-50 microM), by attenuating the melanin production, intracellular tyrosinase activity and tyrosinase expression. 1-Methyl-3-isobutylxanthine 130-134 tyrosinase Mus musculus 308-318