Title : Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.

Pub. Date : 2019 Jan 17

PMID : 30472117






1 Functional Relationships(s)
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1 We have used biophysical measurements and X-ray crystallography to investigate the ATP-competitive inhibitor binding properties of cyclin-free and cyclin-bound CDK1 and CDK2. Adenosine Triphosphate cyclin dependent kinase 1 Homo sapiens