Title : Donepezil improves neuropathy through activation of AMPK signalling pathway in streptozotocin-induced diabetic mice.

Pub. Date : 2019 Jan

PMID : 30414938






3 Functional Relationships(s)
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1 Donepezil improves neuropathy through activation of AMPK signalling pathway in streptozotocin-induced diabetic mice. Donepezil protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 Donepezil can activate AMPK and exerts neuroprotective effects. Donepezil protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
3 Donepezil, an AMPK activator, blocked the phosphorylation of AKT/MAPK/4EBP1, down regulate the expression of NMDA receptors and reversed hyperalgesia developed in diabetic mice. Donepezil protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens