Pub. Date : 2018 Nov 10
PMID : 30318120
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p-Coumaric acid stimulates longitudinal bone growth through increasing the serum production and expression levels of insulin-like growth factor 1 in rats. | Coumaric Acids | insulin-like growth factor 1 | Rattus norvegicus |
| 2 | Expression of insulin-like growth factor 1 and its receptor in the proliferative and hypertrophic zones, and serum levels of growth hormone and insulin-like growth factor 1 were significantly increased as well in the p-coumaric acid-treated group. | Coumaric Acids | insulin-like growth factor 1 | Rattus norvegicus |
| 3 | Expression of insulin-like growth factor 1 and its receptor in the proliferative and hypertrophic zones, and serum levels of growth hormone and insulin-like growth factor 1 were significantly increased as well in the p-coumaric acid-treated group. | Coumaric Acids | insulin-like growth factor 1 | Rattus norvegicus |
| 4 | Via increasing both the serum level of insulin-like growth factor 1 and its expression, p-coumaric acid could promote cell proliferation in growth plate zones. | Coumaric Acids | insulin-like growth factor 1 | Rattus norvegicus |