Pub. Date : 2018 Dec
PMID : 30205091
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Methadone undergoes N-demethylation by multiple cytochrome P450 (CYP) enzymes including CYP3A4, CYP2B6, CYP2C19, CYP2D6, CYP2C9, and CYP2C8. | Methadone | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | In vivo, polymorphism effects on methadone systemic exposure have been noted for CYP2B6, CYP3A4, and CYP2D6. | Methadone | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |