Title : Elobixibat, the first-in-class Ileal Bile Acid Transporter inhibitor, for the treatment of Chronic Idiopathic Constipation.

Pub. Date : 2018 Aug

PMID : 30129377






1 Functional Relationships(s)
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1 IBAT inhibitors block ileal absorption of bile acids by: (1) interrupting the enterohepatic circulation of bile resulting in a fall in serum cholesterol and (2) increasing the delivery of bile acids into the colon. Cholesterol solute carrier family 10 member 2 Homo sapiens