Pub. Date : 2018 Aug 6
PMID : 30086303
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Importantly, ATF6 containing a luminal achromatopsia eye disease mutation, unresponsive to proteotoxic stress, can be activated by fenretinide, a drug that upregulates DHC, suggesting a potential therapy for this and other ATF6-related diseases including heart disease and stroke. | Fenretinide | activating transcription factor 6 | Homo sapiens |
2 | Importantly, ATF6 containing a luminal achromatopsia eye disease mutation, unresponsive to proteotoxic stress, can be activated by fenretinide, a drug that upregulates DHC, suggesting a potential therapy for this and other ATF6-related diseases including heart disease and stroke. | Fenretinide | activating transcription factor 6 | Homo sapiens |