Pub. Date : 2018 Oct
PMID : 30066934
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of cFLIP overcomes acquired resistance to sorafenib via reducing ER stress-related autophagy in hepatocellular carcinoma. | Sorafenib | CASP8 and FADD like apoptosis regulator | Homo sapiens |
| 2 | The knockdown of cFLIP reversed the acquired sorafenib resistance by activating caspase-8 and inhibiting activated ERS in the sorafenib-resistant HCC cells. | Sorafenib | CASP8 and FADD like apoptosis regulator | Homo sapiens |
| 3 | The knockdown of cFLIP reversed the acquired sorafenib resistance by activating caspase-8 and inhibiting activated ERS in the sorafenib-resistant HCC cells. | Sorafenib | CASP8 and FADD like apoptosis regulator | Homo sapiens |
| 4 | In conclusion, cFLIP was identified as a potential target for overcoming the acquired sorafenib resistance in HCC. | Sorafenib | CASP8 and FADD like apoptosis regulator | Homo sapiens |