Title : Renal sodium and magnesium reabsorption are not coupled in a mouse model of Gordon syndrome.

Pub. Date : 2018 Jul

PMID : 30030908






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In this model, DCT1-specific expression of a constitutively active mutant form of the NCC-phosphorylating kinase, SPAK (CA-SPAK), increases NCC activity and hydrochlorothiazide (HCTZ)-sensitive Na+ reabsorption. Hydrochlorothiazide solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 Mus musculus
2 In this model, DCT1-specific expression of a constitutively active mutant form of the NCC-phosphorylating kinase, SPAK (CA-SPAK), increases NCC activity and hydrochlorothiazide (HCTZ)-sensitive Na+ reabsorption. Hydrochlorothiazide solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 Mus musculus