| Protein Name | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18174 |
| Gene Symbol | Slc11a2 |
| UniProt | P49282 (NRAM2_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
69
Total Number of Articles : 159 |
Description |
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 |
| Gene Summary |
Enables cobalt ion transmembrane transporter activity; ferrous iron transmembrane transporter activity; and proton transmembrane transporter activity. Acts upstream of or within several processes, including cation transport; erythrocyte development; and multicellular organismal iron ion homeostasis. Located in several cellular components, including brush border membrane; endosome; and extracellular vesicle. Is integral component of plasma membrane. Is expressed in embryo; intestine; small intestine; and yolk sac. Human ortholog(s) of this gene implicated in Parkinson's disease; amyotrophic lateral sclerosis; anemia; and hypochromic anemia. Orthologous to human SLC11A2 (solute carrier family 11 member 2). [provided by Alliance of Genome Resources, Apr 2022] |
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