Title : Impact of ABCB1 genotype in Collies on the pharmacokinetics of R- and S-fexofenadine.

Pub. Date : 2018 Dec

PMID : 30020547






1 Functional Relationships(s)
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1 Thirty-two Collies were used to determine the impact of ABCB1 genotype and phenotype on the plasma pharmacokinetics of fexofenadine"s (Fex) R- and S-enantiomers after bolus Fex administration, as human P-gp exhibits stereoselectivity. fexofenadine ATP binding cassette subfamily B member 1 Homo sapiens