Title : Targeting mitochondria with folic acid and vitamin B12 ameliorates nicotine mediated islet cell dysfunction.

Pub. Date : 2018 Sep

PMID : 29972271






1 Functional Relationships(s)
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1 Simultaneously, nicotine induces pancreatic islet cell apoptosis by modulating DeltaPsim via increased cytosolic Ca2+ level, altered Bcl-2, Bax, cytochrome c, caspase-9, PARP expressions which were prevented by the supplementation of folic acid and vitamin B12 . Nicotine BCL2 apoptosis regulator Homo sapiens