Pub. Date : 2018 Nov
PMID : 29957877
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Estradiol-mediated regulation of hepatic iNOS in obese rats: Impact of Src, ERK1/2, AMPKalpha, and miR-221. | Estradiol | nitric oxide synthase 2 | Rattus norvegicus |
2 | PURPOSE: This study aimed to investigate in vivo effects of estradiol on the regulation of hepatic inducible nitric oxide synthase (iNOS) expression in the high fat (HF) diet-induced obesity. | Estradiol | nitric oxide synthase 2 | Rattus norvegicus |
3 | PURPOSE: This study aimed to investigate in vivo effects of estradiol on the regulation of hepatic inducible nitric oxide synthase (iNOS) expression in the high fat (HF) diet-induced obesity. | Estradiol | nitric oxide synthase 2 | Rattus norvegicus |
4 | Results show that estradiol treatment of HF rats decreased hepatic iNOS mRNA (P < 0.05) and protein expression (P < 0.01), the protein levels of p65 subunit of nuclear factor kappaB (P < 0.05) and ERalpha (P < 0.05), ERK1/2 phosphorylation (P < 0.001), and ERalpha/Src kinase association (P < 0.05). | Estradiol | nitric oxide synthase 2 | Rattus norvegicus |