Title : src kinase catalyzes the phosphorylation and activation of the insulin receptor kinase.

Pub. Date : 1985 May 10

PMID : 2985615






2 Functional Relationships(s)
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Protein Name
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1 When a partially purified insulin receptor preparation immobilized on insulin-agarose is incubated with [gamma-32P]ATP, Mn2+, and Mg2+ ions, the receptor beta subunit becomes 32P-labeled. Sepharose insulin receptor Homo sapiens
2 Subsequent to src kinase-mediated tyrosine phosphorylation, the insulin receptor, either immobilized on insulin-agarose or in detergent extracts, exhibits a 2-fold increase in associated kinase activity using histone as substrate. Sepharose insulin receptor Homo sapiens