Title : Reactive oxygen species mediates 50-Hz magnetic field-induced EGF receptor clustering via acid sphingomyelinase activation.

Pub. Date : 2018 Jul

PMID : 29659325






3 Functional Relationships(s)
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1 In the present experiment, the possible roles of reactive oxygen species (ROS) in MF-induced EGFR clustering were investigated. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens
2 However, pretreatment with NAC or PDTC, the scavenger of ROS, not only counteracted the effects of a 50-Hz MF on ROS level and AMS activity, but also inhibited the EGFR clustering induced by MF exposure. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens
3 CONCLUSIONS: The present and previous data suggest that ROS mediates the MF-induced EGFR clustering via ASMase activation. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens