Pub. Date : 2018 Jun
PMID : 29605894
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Since EPHX1 enzyme is essential in cellular defense against epoxides, the diminished enzymatic activity conferred by the variant allele C could explain the risk associations found for i-AML. | Epoxy Compounds | epoxide hydrolase 1 | Homo sapiens |
| 2 | In conclusion, EPHX1 rs1051740 plays an important role in i-AML"s genetic susceptibility by modulating the carcinogenic effects of epoxide exposures in the bone marrow. | Epoxy Compounds | epoxide hydrolase 1 | Homo sapiens |