| Protein Name | epoxide hydrolase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 2052 |
| Gene Symbol | EPHX1 |
| UniProt | P07099 (HYEP_HUMAN), R4SBI6 (R4SBI6_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
332
Total Number of Articles : 405 |
Description |
epoxide hydrolase 1 |
| Gene Summary |
Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2008] |
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