Title : Direct inhibitory effect of atriopeptin III on renin release in primate kidney.

Pub. Date : 1987 Jul 20

PMID : 2955183






4 Functional Relationships(s)
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1 Similarly, the incubation of the superficial cortical slices with arachidonic acid (10(-3) M) resulted in a 4-fold increase in tissue renin release which was blocked by the calcium ionophore A23187 (17 X 10(-6) M) and ANP; interestingly, DDA did not block arachidonic acid-induced renin release. Calcimycin renin Rattus norvegicus
2 Similarly, the incubation of the superficial cortical slices with arachidonic acid (10(-3) M) resulted in a 4-fold increase in tissue renin release which was blocked by the calcium ionophore A23187 (17 X 10(-6) M) and ANP; interestingly, DDA did not block arachidonic acid-induced renin release. Calcimycin renin Rattus norvegicus
3 Further, the inhibitory action of A23187 on renin release suggests, as in other species, an integral role for intracellular calcium in the renin release process. Calcimycin renin Rattus norvegicus
4 Further, the inhibitory action of A23187 on renin release suggests, as in other species, an integral role for intracellular calcium in the renin release process. Calcimycin renin Rattus norvegicus