Pub. Date : 2017 Dec 19
PMID : 29257079
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sulfuretin Attenuates MPP+-Induced Neurotoxicity through Akt/GSK3beta and ERK Signaling Pathways. | sulfuretin | glycogen synthase kinase 3 beta | Homo sapiens |
| 2 | Moreover, sulfuretin significantly increased the phosphorylation of Akt, GSK3beta, and ERK. | sulfuretin | glycogen synthase kinase 3 beta | Homo sapiens |
| 3 | An inhibitor of GSK3beta mimicked sulfuretin-induced protection against MPP+. | sulfuretin | glycogen synthase kinase 3 beta | Homo sapiens |
| 4 | Taken together, these results suggest that sulfuretin significantly attenuates MPP+-induced neurotoxicity through Akt/GSK3beta and ERK signaling pathways in SH-SY5Y cells. | sulfuretin | glycogen synthase kinase 3 beta | Homo sapiens |