Pub. Date : 2017 Nov 30
PMID : 29214238
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The activity of SHP2, like that of most PTPs, is reversibly inactivated by reactive oxygen species (ROS). | Reactive Oxygen Species | protein tyrosine phosphatase non-receptor type 11 | Homo sapiens |
2 | The activity of SHP2, like that of most PTPs, is reversibly inactivated by reactive oxygen species (ROS). | Reactive Oxygen Species | protein tyrosine phosphatase non-receptor type 11 | Homo sapiens |
3 | However, the molecular basis of this inactivation and the consequences of NS-related mutations in PTPN11 on ROS-mediated inhibition are poorly understood. | Reactive Oxygen Species | protein tyrosine phosphatase non-receptor type 11 | Homo sapiens |