Title : Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade.

Pub. Date : 2017 Oct 15

PMID : 29138276






1 Functional Relationships(s)
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1 Specifically, we found that survival of cancer cells was critically dependent on phospholipase A2 (PLA2) to mobilize lysophospholipids and free fatty acids to sustain fatty acid oxidation and oxidative phosphorylation. Fatty Acids, Nonesterified phospholipase A2 group IB Homo sapiens