Title : New insights of subfertility among transplanted women: Immunosuppressive drug FK506 leads to calcium leak and oocyte activation before fertilization.

Pub. Date : 2018 Mar

PMID : 29131377






1 Functional Relationships(s)
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1 These findings identify the previously unknown role of FKBP12 in female reproduction which contributes to the release of calcium via IP3 R channel and might open up new strategies for women who want to bear a baby after transplantation. Calcium inositol 1,4,5-trisphosphate receptor type 3 Homo sapiens