| Protein Name | inositol 1,4,5-trisphosphate receptor type 3 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3710 |
| Gene Symbol | ITPR3 |
| UniProt | Q14573 (ITPR3_HUMAN), A6H8K3 (A6H8K3_HUMAN), Q59ES2 (Q59ES2_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
329
Total Number of Articles : 635 |
Description |
inositol 1,4,5-trisphosphate receptor type 3 |
| Gene Summary |
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010] |
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