Pub. Date : 2018 Jan 1
PMID : 29074603
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Decrease in Mcl-1 protein expression was abrogated by treatment with the proteasome inhibitor MG132, and was preceded by downregulation of the Mcl-1 deubiquitinase USP9X, a novel mechanism of Mcl-1 regulation in AML.Conclusions: The data support clinical testing of Pim and FLT3 inhibitor combination therapy for FLT3-ITD AML. | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |