Title : Dihydrocapsaicin Attenuates Blood Brain Barrier and Cerebral Damage in Focal Cerebral Ischemia/Reperfusion via Oxidative Stress and Inflammatory.

Pub. Date : 2017 Sep 5

PMID : 28874782






2 Functional Relationships(s)
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1 DHC also activated nuclear-related factor-2 (Nrf2) which involves antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase (GPx), and significantly decreased oxidative stress and inflammation via down-regulated reactive oxygen species (ROS), NADPH oxidase (NOX2, NOX4), nuclear factor kappa-beta (NF-kB), and nitric oxide (NO), including matrix metalloproteinases-9 (MMP-9) levels. dihydrocapsaicin superoxide dismutase 1 Homo sapiens
2 DHC also activated nuclear-related factor-2 (Nrf2) which involves antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase (GPx), and significantly decreased oxidative stress and inflammation via down-regulated reactive oxygen species (ROS), NADPH oxidase (NOX2, NOX4), nuclear factor kappa-beta (NF-kB), and nitric oxide (NO), including matrix metalloproteinases-9 (MMP-9) levels. dihydrocapsaicin superoxide dismutase 1 Homo sapiens