Title : Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury.

Pub. Date : 2017 Oct 1

PMID : 28733206






1 Functional Relationships(s)
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1 The increases in ceramide concentrations may induce ER stress and activate the JNK pathway by affecting the expression of the related genes, and eventually trigger the mitochondria-independent apoptosis in hepatocytes. Ceramides mitogen-activated protein kinase 8 Homo sapiens