Title : Neuroprotective Effects of Pycnogenol Against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury in Primary Rat Astrocytes via NF-κB and ERK1/2 MAPK Pathways.

Pub. Date : 2017

PMID : 28662519






1 Functional Relationships(s)
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1 Similarly to PYC, NF-kappaB inhibitor PDTC and ERK1/2 inhibitor PD098059 dramatically inhibited OGD/R-induced NF-kappaB activation, ERK1/2 phosphorylation, and ROS production, as well as TNF-alpha secretion. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one tumor necrosis factor Rattus norvegicus