Title : Semisynthesis and biological evaluation of prenylated resveratrol derivatives as multi-targeted agents for Alzheimer's disease.

Pub. Date : 2017 Oct

PMID : 28600778






1 Functional Relationships(s)
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1 A series of prenylated resveratrol derivatives were designed, semisynthesized and biologically evaluated for inhibition of beta-secretase (BACE1) and amyloid-beta (Abeta) aggregation as well as free radical scavenging and neuroprotective and neuritogenic activities, as potential novel multifunctional agents against Alzheimer"s disease (AD). Resveratrol beta-secretase 1 Homo sapiens