Pub. Date : 2017 Oct 5
PMID : 28581516
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Although the drug targeting inactivation of tumor suppressors by DNA methylation had little effect, the inhibition of Mek, a K-Ras effector, in combination with the standard of care (chemotherapy consisting of gemcitabine/Nab-paclitaxel), reduced the growth of three out of five PC-PDXs and impaired metastasis. | nab | mitogen-activated protein kinase kinase 7 | Homo sapiens |
| 2 | Together with the gemcitabine/Nab-paclitaxel backbone, Mek inhibition could be effective in treatment of PC. | nab | mitogen-activated protein kinase kinase 7 | Homo sapiens |