PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28581516-4 2017 Although the drug targeting inactivation of tumor suppressors by DNA methylation had little effect, the inhibition of Mek, a K-Ras effector, in combination with the standard of care (chemotherapy consisting of gemcitabine/Nab-paclitaxel), reduced the growth of three out of five PC-PDXs and impaired metastasis. nab 222-225 mitogen-activated protein kinase kinase 7 Homo sapiens 118-121 28581516-9 2017 Together with the gemcitabine/Nab-paclitaxel backbone, Mek inhibition could be effective in treatment of PC. nab 30-33 mitogen-activated protein kinase kinase 7 Homo sapiens 55-58