Title : Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells.

Pub. Date : 2017 Jun 20

PMID : 28467797






2 Functional Relationships(s)
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1 Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells. 5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide interleukin 6 Homo sapiens
2 KY-05009 and dovitinib synergistically inhibited interleukin-6-stimulated proliferation and induced apoptosis through the inhibition of Wnt signaling in MM cells. 5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide interleukin 6 Homo sapiens