Title : Norepinephrine regulates cocaine-primed reinstatement via α1-adrenergic receptors in the medial prefrontal cortex.

Pub. Date : 2017 Jun

PMID : 28392265






2 Functional Relationships(s)
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1 Cocaine-primed reinstatement can also be attenuated by systemic administration of dopamine beta-hydroxylase (DBH) inhibitors, which prevent norepinephrine (NE) synthesis, or by alpha1-adrenergic receptor (alpha1AR) antagonists, indicating functional modulation by the noradrenergic system. Norepinephrine dopamine beta-hydroxylase Rattus norvegicus
2 Cocaine-primed reinstatement can also be attenuated by systemic administration of dopamine beta-hydroxylase (DBH) inhibitors, which prevent norepinephrine (NE) synthesis, or by alpha1-adrenergic receptor (alpha1AR) antagonists, indicating functional modulation by the noradrenergic system. Norepinephrine dopamine beta-hydroxylase Rattus norvegicus