Title : Nuclear lamins and progerin are dispensable for antioxidant Nrf2 response to arsenic and cadmium.

Pub. Date : 2017 May

PMID : 28229933






2 Functional Relationships(s)
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1 We investigated the activation of nuclear factor-E2-related factor 2 (Nrf2) which regulates various antioxidant genes including heme oxygenase-1 (HMOX1), following exposure to sodium arsenite or cadmium chloride in lamin knockdown human cell lines and primary HGPS human fibroblasts. sodium arsenite heme oxygenase 1 Homo sapiens
2 We investigated the activation of nuclear factor-E2-related factor 2 (Nrf2) which regulates various antioxidant genes including heme oxygenase-1 (HMOX1), following exposure to sodium arsenite or cadmium chloride in lamin knockdown human cell lines and primary HGPS human fibroblasts. sodium arsenite heme oxygenase 1 Homo sapiens