Title : Demethyleneberberine alleviates inflammatory bowel disease in mice through regulating NF-κB signaling and T-helper cell homeostasis.

Pub. Date : 2017 Feb

PMID : 27900412






2 Functional Relationships(s)
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1 RESULTS: In vivo, DMB significantly alleviated the weight loss and diminished myeloperoxidase (MPO) activity, while significantly reduced the production of pro-inflammatory cytokines, such as interleukin (IL)-6 and tumor necrosis factor-alpha (TNF-alpha), and inhibited the activation of NF-kappaB signaling pathway. demethyleneberberine tumor necrosis factor Mus musculus
2 RESULTS: In vivo, DMB significantly alleviated the weight loss and diminished myeloperoxidase (MPO) activity, while significantly reduced the production of pro-inflammatory cytokines, such as interleukin (IL)-6 and tumor necrosis factor-alpha (TNF-alpha), and inhibited the activation of NF-kappaB signaling pathway. demethyleneberberine tumor necrosis factor Mus musculus