Title : Possible involvement of iNOS and TNF-α in nutritional intervention against nicotine-induced pancreatic islet cell damage.

Pub. Date : 2016 Dec

PMID : 27832994






3 Functional Relationships(s)
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1 Possible involvement of iNOS and TNF-alpha in nutritional intervention against nicotine-induced pancreatic islet cell damage. Nicotine tumor necrosis factor Rattus norvegicus
2 Supplementation with folic acid and vitamin B12 suppressed the nicotine induced changes in HbA1c, insulin, TNF-alpha, IL-6, generation of reactive oxygen species, and attenuated the changes in markers of oxidative stress. Nicotine tumor necrosis factor Rattus norvegicus
3 Moreover, folic acid and vitamin B12 also counteracted the increased expression of protein and mRNA contents of TNF-alpha and iNOS produced by nicotine. Nicotine tumor necrosis factor Rattus norvegicus