Pub. Date : 2016 Nov 15
PMID : 27772765
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pretreated duloxetine protects hippocampal CA1 pyramidal neurons from ischemia-reperfusion injury through decreases of glial activation and oxidative stress. | Duloxetine Hydrochloride | carbonic anhydrase 1 | Homo sapiens |
| 2 | In the present study, we investigated the neuroprotective effect of pre-treated DXT in the hippocampal CA1 region following transient global cerebral ischemia. | Duloxetine Hydrochloride | carbonic anhydrase 1 | Homo sapiens |
| 3 | Pre-treatment with 40mg/kg DXT protected pyramidal neurons in the CA1 region from ischemia-reperfusion injury. | Duloxetine Hydrochloride | carbonic anhydrase 1 | Homo sapiens |
| 4 | On the other hand, we found that pre-treatment with DXT did not increase 4-hydroxy-2-noneal (a marker for lipid peroxidation) and significantly increased the expression of Cu, Zn-superoxide dismutase, an antioxidant, in the CA1 pyramidal neurons compared with non-treated those after ischemia-reperfusion. | Duloxetine Hydrochloride | carbonic anhydrase 1 | Homo sapiens |