Protein Name carbonic anhydrase 1
Organism Homo sapiens
Gene ID 759
Gene Symbol


UniProt P00915 (CAH1_HUMAN), V9HWE3 (V9HWE3_HUMAN)
Relationships Total Number of functionally related compound(s) : 1391
Total Number of Articles : 2208

carbonic anhydrase 1

Gene Summary

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016]

  • carbonic anhydrase 1
  • carbonate dehydratase I
  • carbonic anhydrase B
Click to show/hide the synonyms