Title : Distinct Immunoregulatory Mechanisms in Mesenchymal Stem Cells: Role of the Cytokine Environment.

Pub. Date : 2016 Dec

PMID : 27665290






2 Functional Relationships(s)
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1 We found that indomethacine, an inhibitor of cyclooxygenase-2 (Cox-2) activity, completely abrogated the inhibition of IL-10 production in cultures containing MSCs and IFN-gamma, but had no effect on the suppression in cell cultures containing MSCs and IL-4. Indomethacin prostaglandin-endoperoxide synthase 2 Homo sapiens
2 We found that indomethacine, an inhibitor of cyclooxygenase-2 (Cox-2) activity, completely abrogated the inhibition of IL-10 production in cultures containing MSCs and IFN-gamma, but had no effect on the suppression in cell cultures containing MSCs and IL-4. Indomethacin prostaglandin-endoperoxide synthase 2 Homo sapiens