Title : Stimulation of thrombin- and plasmin-mediated activation of thrombin-activatable fibrinolysis inhibitor by anionic molecules.

Pub. Date : 2016 Oct

PMID : 27564657






2 Functional Relationships(s)
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1 METHODS: TAFI activation by thrombin or plasmin was studied in the presence of physiological anionic molecules (polyphosphate, heparin, hyaluronan, DNA and dermatan sulfate) and the non-physiological sodium dodecyl sulfate (SDS). Dermatan Sulfate carboxypeptidase B2 Homo sapiens
2 Dermatan sulfate and polyphosphates with sodium as counter ion (Na-PolyP700, Na-PolyP100 and Na-PolyP70) enhanced plasmin-mediated but not thrombin-mediated TAFI activation. Dermatan Sulfate carboxypeptidase B2 Homo sapiens