Pub. Date : 2016 Jun 13
PMID : 27296779
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: It is essential to determine the specificity of AV-1451 PET for tau in brain imaging by using pathological comparisons. | 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole | microtubule associated protein tau | Homo sapiens |
| 2 | We performed autoradiography in autopsy-confirmed Alzheimer disease and other neurodegenerative disorders to evaluate the specificity of AV-1451 binding for tau aggregates. | 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole | microtubule associated protein tau | Homo sapiens |
| 3 | The strength of AV-1451 binding with respect to tau isoforms in various neurodegenerative disorders was: 3R + 4R tau (e.g., AD) > 3R tau (e.g., Pick disease) or 4R tau. | 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole | microtubule associated protein tau | Homo sapiens |
| 4 | The strength of AV-1451 binding with respect to tau isoforms in various neurodegenerative disorders was: 3R + 4R tau (e.g., AD) > 3R tau (e.g., Pick disease) or 4R tau. | 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole | microtubule associated protein tau | Homo sapiens |
| 5 | The strength of AV-1451 binding with respect to tau isoforms in various neurodegenerative disorders was: 3R + 4R tau (e.g., AD) > 3R tau (e.g., Pick disease) or 4R tau. | 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole | microtubule associated protein tau | Homo sapiens |
| 6 | The strength of AV-1451 binding with respect to tau isoforms in various neurodegenerative disorders was: 3R + 4R tau (e.g., AD) > 3R tau (e.g., Pick disease) or 4R tau. | 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole | microtubule associated protein tau | Homo sapiens |