PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27296779-1 2016 BACKGROUND: It is essential to determine the specificity of AV-1451 PET for tau in brain imaging by using pathological comparisons. 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 60-67 microtubule associated protein tau Homo sapiens 76-79 27296779-2 2016 We performed autoradiography in autopsy-confirmed Alzheimer disease and other neurodegenerative disorders to evaluate the specificity of AV-1451 binding for tau aggregates. 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 137-144 microtubule associated protein tau Homo sapiens 157-160 27296779-6 2016 The strength of AV-1451 binding with respect to tau isoforms in various neurodegenerative disorders was: 3R + 4R tau (e.g., AD) > 3R tau (e.g., Pick disease) or 4R tau. 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 16-23 microtubule associated protein tau Homo sapiens 48-51 27296779-6 2016 The strength of AV-1451 binding with respect to tau isoforms in various neurodegenerative disorders was: 3R + 4R tau (e.g., AD) > 3R tau (e.g., Pick disease) or 4R tau. 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 16-23 microtubule associated protein tau Homo sapiens 113-116 27296779-6 2016 The strength of AV-1451 binding with respect to tau isoforms in various neurodegenerative disorders was: 3R + 4R tau (e.g., AD) > 3R tau (e.g., Pick disease) or 4R tau. 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 16-23 microtubule associated protein tau Homo sapiens 113-116 27296779-6 2016 The strength of AV-1451 binding with respect to tau isoforms in various neurodegenerative disorders was: 3R + 4R tau (e.g., AD) > 3R tau (e.g., Pick disease) or 4R tau. 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 16-23 microtubule associated protein tau Homo sapiens 113-116