Pub. Date : 2016
PMID : 27274503
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of folic acid on homocysteine and insulin resistance of overweight and obese children and adolescents. | Folic Acid | insulin | Homo sapiens |
| 2 | BACKGROUND: Considering the increasing trend of childhood obesity and subsequent burden of the disease in Iran and other countries and importance of early life intervention for achieving sustained effect on health of children and adolescents, this study aimed to investigate the effect of two different dose of folic acid on homocysteine (Hcy) level and insulin resistance of obese children. | Folic Acid | insulin | Homo sapiens |
| 3 | After folic acid administration, mean of Hcy, insulin resistance and insulin decreased significantly in two groups which folic acid administrated with two different doses (P < 0.05). | Folic Acid | insulin | Homo sapiens |
| 4 | CONCLUSION: The findings of current trial showed that folic acid in two studied doses could be a safe and effective supplement for obese children to reduce Hcy level and insulin resistance, which consequently could prevent obesity-related complications including cardiovascular and metabolic disorders. | Folic Acid | insulin | Homo sapiens |