PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27274503-0 2016 Effect of folic acid on homocysteine and insulin resistance of overweight and obese children and adolescents. Folic Acid 10-20 insulin Homo sapiens 41-48 27274503-1 2016 BACKGROUND: Considering the increasing trend of childhood obesity and subsequent burden of the disease in Iran and other countries and importance of early life intervention for achieving sustained effect on health of children and adolescents, this study aimed to investigate the effect of two different dose of folic acid on homocysteine (Hcy) level and insulin resistance of obese children. Folic Acid 311-321 insulin Homo sapiens 354-361 27274503-7 2016 After folic acid administration, mean of Hcy, insulin resistance and insulin decreased significantly in two groups which folic acid administrated with two different doses (P < 0.05). Folic Acid 121-131 insulin Homo sapiens 46-76 27274503-11 2016 CONCLUSION: The findings of current trial showed that folic acid in two studied doses could be a safe and effective supplement for obese children to reduce Hcy level and insulin resistance, which consequently could prevent obesity-related complications including cardiovascular and metabolic disorders. Folic Acid 54-64 insulin Homo sapiens 170-177