Pub. Date : 2016 Aug
PMID : 27207556
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A Glycine-Insulin Autocrine Feedback Loop Enhances Insulin Secretion From Human beta-Cells and Is Impaired in Type 2 Diabetes. | Glycine | insulin | Homo sapiens |
| 2 | A Glycine-Insulin Autocrine Feedback Loop Enhances Insulin Secretion From Human beta-Cells and Is Impaired in Type 2 Diabetes. | Glycine | insulin | Homo sapiens |
| 3 | beta-Cells exhibit significant glycine-induced Cl(-) currents that promote membrane depolarization, Ca(2+) entry, and insulin secretion from beta-cells from donors without T2D. | Glycine | insulin | Homo sapiens |
| 4 | Finally, a significant positive relationship exists between insulin and GlyR, because insulin enhances the glycine-activated current in a phosphoinositide 3-kinase-dependent manner, a positive feedback loop that we find is completely lost in beta-cells from donors with T2D. | Glycine | insulin | Homo sapiens |
| 5 | Finally, a significant positive relationship exists between insulin and GlyR, because insulin enhances the glycine-activated current in a phosphoinositide 3-kinase-dependent manner, a positive feedback loop that we find is completely lost in beta-cells from donors with T2D. | Glycine | insulin | Homo sapiens |